Prolyl endopeptidase and thrombin inhibitory diterpenoids from the bark of Xylopia aethiopica.
نویسندگان
چکیده
The inhibitory effects of seven diterpenes, belonging to three different structural classes and isolated from the bark of Xylopia aethiopica, were investigated against the enzymes prolyl endopeptidase (PEP) and alpha-thrombin. Five compounds exhibited inhibitory activity against them.
منابع مشابه
Structure elucidation and chemistry of novel diterpenoids from Euphorbia plants of Iran
Plants of the genus Euphorbia have been investigated for different bioactive natural products. I have isolated several new and bioactive diterpenoids from different species of Euphorbia of Iran with myrsinane type skeleton. The structure of the compounds was determined using high resolution mass spectroscopy, 1 D and 2 D NMR spectral data. The stereochemistry of the diterpenoids was determined ...
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 69 9 شماره
صفحات -
تاریخ انتشار 2005